منابع مشابه
A Peculiar Pigmentary Condition
History.?In October 1910, the patient, Sepoy T. K., 27th Punjabis, showed me some pigmented spots on iiis face, hands and left leg. They first appeared in March, 1U0S, when the patient was living in Jhandola. He believed that quinine, which he was taking prophylactically at that time, caused their appearance. No fresh spots have appeared since then, but some of the original areas have increased...
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Many factors have been implicated for the etiology of melasma, but the exact cause of this hypermelanosis is poorly understood. However, it is considered to result from solar radiation and genetic predisposition. Moreover, pregnancy, oral contraception and hormone replacement therapy with natural and synthetic oestrogens, have been involved in the pathogenesis of this hypemelanosis. Despite the...
متن کاملPigmentary dispersion.
A long-term study of primary pigmentary dispersion has shown that the condition is commoner in males than females and appears most frequently in the third decade. After 10 years there may be a significant reduction in the amount of pigment deposited on the cornea, and the condition of several patients receiving treatment for glaucoma has remained under control when treatment has been stopped.
متن کاملMitochondrial Preprotein Translocase of Trypanosomatids Has a Bacterial Origin
Mitochondria are found in all eukaryotic cells and derive from a bacterial endosymbiont [1, 2]. The evolution of a protein import system was a prerequisite for the conversion of the endosymbiont into a true organelle. Tom40, the essential component of the protein translocase of the outer membrane, is conserved in mitochondria of almost all eukaryotes but lacks bacterial orthologs [3-6]. It serv...
متن کاملThe neurofibroma in von Recklinghausen neurofibromatosis has a unicellular origin.
von Recklinghausen neurofibromatosis (NF1) is the most common hereditary syndrome predisposing to neoplasia. NF1 is an autosomal dominant disease caused by a single gene which maps to chromosome 17q11.2. The most common symptomatic manifestation of NF1 is the benign neurofibroma. Our previous studies of tumors in NF1, studies which detected a loss of heterozygosity for DNA markers from the NF1 ...
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ژورنال
عنوان ژورنال: The Lancet
سال: 1922
ISSN: 0140-6736
DOI: 10.1016/s0140-6736(01)00612-2